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AlphaFold 3

AlphaFold 3 is a biomolecular structure prediction system developed jointly by Google DeepMind and Isomorphic Labs and published in Nature on May 8, 2024.

AI ModelsDrug Discovery

AlphaGenome

AlphaGenome is a unified deep learning model developed by Google DeepMind that predicts thousands of functional genomic properties from raw DNA sequences.

AI ModelsGoogle DeepMind

AlphaGeometry

AlphaGeometry is a neuro-symbolic artificial intelligence system developed by Google DeepMind that solves competition-level geometry problems at a standard comparable to human Olympiad gold medalists.

AI ModelsGoogle DeepMind

AlphaProof

AlphaProof is a reinforcement-learning system from Google DeepMind that finds and verifies formal mathematical proofs in the Lean 4 theorem prover

AI ModelsGoogle DeepMind

AlphaProteo

AlphaProteo is a machine learning system developed by Google DeepMind for the de novo design of high-affinity protein binders, novel proteins that attach tightly to a chosen target.

AI ModelsDrug Discovery

Boltz

Boltz is a family of open-source biomolecular structure prediction models developed primarily at MIT's Computer Science and Artificial Intelligence Laboratory (CSAIL) and the MIT Jameel Clinic.

AI ModelsDrug Discovery

Boltz-2

Boltz-2 is an open-source biomolecular foundation model that jointly predicts the 3D structure of biological complexes and the binding affinity between small molecules and proteins.

AI ModelsOpen Source AI

Chai-1

Chai-1 is an open multimodal foundation model for biomolecular structure prediction released by the San Francisco startup Chai Discovery on 9 September 2024.

AI ModelsDrug Discovery

Chai-2

Chai-2 is a generative artificial intelligence model from Chai Discovery for designing antibodies and small protein binders from scratch.

AI ModelsGenerative AI

ESMFold

ESMFold is a protein structure prediction model developed by the Meta AI Fundamental AI Research (FAIR) Protein Team.

AI ModelsMeta AI

MatterGen

MatterGen is a generative artificial intelligence model from Microsoft Research for designing novel inorganic crystalline materials.

AI Models

NVIDIA Earth-2

NVIDIA Earth-2 is a software platform and family of models from NVIDIA for AI-accelerated weather and climate simulation, prediction, and visualization.

AI Models

State (Arc Institute virtual cell model)

State is a machine learning "virtual cell" model developed by the Arc Institute, a nonprofit biomedical research organization, to predict how cells respond to perturbations such as drugs, cytokines, and…

AI Models

WeatherNext 2

WeatherNext 2 is an artificial intelligence weather forecasting model from Google DeepMind and Google Research, announced on November 17, 2025

AI Models

rBio (CZI)

rBio (styled rbio1 in the accompanying preprint) is a biological reasoning large language model released by the Chan Zuckerberg Initiative (CZI) on August 21, 2025.

AI Models